SIMBIOEN INSILCO TESTING PANEL our integrated services GENOMICS PANEL 16S & 18S Fingerprinting, NGS: Metagenomics, WGS, Exome, RNA-Seq, ChIP Sequencing genome annotation Identification and annotation of genomic features such as genes, and non-coding regions. insilco gene mutation Computational models to predict the effects of gene mutations, genetic variations and their potential impact. protein modelling Rendering of 3D models of protein structures, enabling the study of protein function, interactions, and drug binding sites protein simulation analysis Simulation of the dynamic behavior of proteins over time for studying their conformational changes, stability, and interaction mechanisms insilco protein mutation Structural and functional Analysis of protein mutations, providing insights into their role in diseases and potential therapeutic targets. network pharmacology Interactions between drugs, targets, and biological networks for identification of multi-target effects and optimization of targets transcriptomics Analysis of RNA transcripts conversion to gene expression patterns, regulatory mechanisms, and functional genomics in various conditions metabolomics Comprehensive profile of metabolites using Gene Clustering Techniques with Whole genome Data for targeted drug delivery cheminformatics Physiochemical property prediction, Spectral data prediction UV, FTIR, NMR, Bioactivity and Target prediction virtual library screening Screening of large libraries of compounds using ADME based computational methods for identification of lead molecule qsar modelling Development of Molecular descriptor based structural models to identify compounds with biological activity pharmacophore modelling Developmental of structural core with essential molecular features aiding in the design of compounds with desired biological activities toxicoinformatics Insilco approach to predict the Cell line, Animal toxicity based LD 50 values of chemical compounds using its structure immunoinformatics computational tools to analyze immune system data for vaccine design, epitope prediction, and understanding immune responses molecular docking Prediction of the preferred orientation and binding affinity of small molecule/peptide with its target protein molecular simulation Dynamics simulation using Gromacs, NAMD, Desmond, MOE, Charm GUI up to 1000 ns using dedicated inhouse serves post md analysis MD Simulation Calculations such as MMGBSA, Principle Component Analysis, RMSD, RMSF, Radius of Gyration, Trajectory Analysis
